Seroprevalence of Toxoplasmosis in Iraqi Patients with Liver Diseases
Abstract
Toxoplasmosis is a parasitic protozoan disease that causes a variety of clinical illnesses, most cases are asymptomatic, and some cause severe problems. The present study was aimed to highlight the relationship between toxoplasmosis and different liver diseases, this study consist of 204 samples of patients suffering from liver disease. Tow diagnostic tests were applied Toxo IgG/IgM rapid cassette test and Enzyme-linked immunosorbent assay (ELISA). In addition, some liver enzymes level were measured Alkaline phosphatase (ALP), Alanine aminotransferase (ALT), and Aspartate aminotransferase (AST) in serum of study samples. Important epidemiological risk factors were also detected. Seroprevalence of toxoplasmosis by using Toxo IgG/IgM rapid cassette test were 50 positive cases with liver disease in 24.5% for IgG antibody, and negative cases were 154 (75.49%) with significant differences. All results were negative for IgM antibodies. ELISA test results were Toxoplasma IgG antibody found in 49 cases with 24% percentage in liver disease patient and 8 positive cases were detected for IgM antibody. Significant elevation of some liver enzyme activities was noticed in patients of Liver disease infected with toxoplasmosis compared with the control group. Positive cases in males were 48.71% and 51.28% in females. High rates of seropositive cases were 43.5% in housemaker patients. Toxoplasma seroprevalence was high in HBV patients, 42.30%.Keywords:
IgG, IgM, Liver diseases, ToxoplasmosisReferences
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